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How Long Does Suboxone Stay in Your System

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  • 8th December 2023

What is Suboxone

Suboxone is a 4:1 combination buprenorphine and naloxone, administered as a replacement for illicit opiates like heroin and morphine.



How long does Suboxone last in your system

Of the two active ingredients of Suboxone, buprenorphine is believed to have an elimination half-life duration between 24 and 60 hours. Naloxone, on the other hand, has an elimination half-life between 2 and 12 hours. Keeping in mind the 5.5 half-life thumb rule, it can be concluded that buprenorphine will take 132-330 hours, or 5 days 12 hours to 13 days and 6 hours to leave your system, while naloxone will take between 11-66 hours.

It can be concluded that around 2 weeks after you take the last dose of Suboxone, its ingredients will be excreted from your system.

How long does Suboxone show up in urine, blood, saliva and hair follicle drug tests

Urine test 40 minutes – 2 weeks
Blood test 2 hours
Saliva test ≤1 week
Hair follicle test 1 – 3 months

It must be noted that not everyone will eliminate Suboxone at the same rate. Factors like the duration and frequency of administration, strength of the dose, and co-administration of other drugs must be considered, as indeed must individual factors like age, build, liver and kidney condition, urinary pH levels, hydration levels, rate of metabolism.

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