How Long Does Naltrexone Stay in Your System

What is naltrexone

Naltrexone is a drug that is used as an opioid antagonist and in the treatment of alcohol and opioid dependence.

How long does naltrexone stay in your system

Naltrexone, once metabolized, produces the metabolite 6-β-naltrexol. To understand how long it will take one’s body to eliminate naltrexone we must consider the half-lives of the parent drug and its metabolite. Naltrexone has an elimination half-life of 4 hours, while the half-life of 6-β-naltrexol is 13 hours.

Keeping the above facts in mind, it can be concluded that both naltrexone and its metabolite will be excreted from your system about 3 days after you last took it.

This timeframe may be shortened or lengthened depending on certain factors like:

• Age of the individual
• Body mass
• Kidney and liver conditions
• Diet
• Hydration levels