How Long Does Hydromorphone Stay in Your System

What is hydromorphone

Hydromorphone, sold primarily under the brand name Dilaudid, is an opioid pain medication.

Hydromorphone

How long does hydromorphone stay in your system after the last dose

While variables like age, health conditions, body-mass, kidney condition, urinary pH have to be taken into consideration, on average, the elimination half-life of intravenous hydromorphone is around 2.3 hours, and oral  hydromorphone has a half-life of 4.1 hours.

Per the 5.5 half-life rule, hydromorphone will be eliminated from the system after the following durations:

Intravenous: 13 hours 45 minutes,

Oral:  22½ hours.