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How Long Does Hydromorphone Stay in Your System

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  • 8th December 2023

What is hydromorphone

Hydromorphone, sold primarily under the brand name Dilaudid, is an opioid pain medication.



How long does hydromorphone stay in your system after the last dose

While variables like age, health conditions, body-mass, kidney condition, urinary pH have to be taken into consideration, on average, the elimination half-life of intravenous hydromorphone is around 2.3 hours, and oral  hydromorphone has a half-life of 4.1 hours.

Per the 5.5 half-life rule, hydromorphone will be eliminated from the system after the following durations:

Intravenous: 13 hours 45 minutes,

Oral:  22½ hours.

How long is hydromorphone detectable in a drug test

Urine test 3-4 days
Blood test Up to 24 hours
Saliva test 1-4 days
Hair follicle test Up to 90 days

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